ML347

MedChem Express

ML347 [1062368-49-3]

10

1062368-49-3

Research Use Only

99.94

C22H16N4O

352.39

ML347 (LDN193719) is a highly selective ALK1 / ALK2 inhibitor. ML347 has IC 50 values of 46 and 32 nM against ALK1 and ALK2, respectively, >300-fold selective over ALK3. ML347 block the phosphorylation of Smad1/5 by TGF-beta1 [1] [2] .

COC1=CC=C(C2=CN3C(N=C2)=C(C4=C5C=CC=NC5=CC=C4)C=N3)C=C1

-20°C,2°C to 8°C

12352200