Bio-Connect

ML404 [1826026-00-9]

HY-114898
MedChem Express
CAS Number1826026-00-9
Product group Chemicals
Molecular Weight328.75
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Overview

  • Supplier
    MedChem Express
  • Product Name
    ML404 [1826026-00-9]
  • Delivery Days Customer
    9
  • CAS Number
    1826026-00-9
  • Certification
    Research Use Only
  • Molecular Formula
    C17H13ClN2O3
  • Molecular Weight
    328.75
  • Scientific Description
    ML404 (Compound 38) is an inhibitor of the mitochondrial permeability transition pore (mtPTP), which can suppress mitochondrial swelling (EC50=4.9 nM) and only disrupts mitochondrial coupling (an adverse effect) at concentrations > 100 microM. ML404 can be utilized in research related to multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), Alzheimers disease (AD), muscular dystrophies (MD), myocardial infarction, and stroke[1].
  • SMILES
    O=C(NC1=CC(Cl)=CC=C1C)C2=NOC(C3=CC=CC(O)=C3)=C2
  • UNSPSC
    12352200