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ML417 [1386162-69-1]

HY-136390
MedChem Express
CAS Number1386162-69-1
Product group Chemicals
Estimated Purity99.50
Molecular Weight379.45
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Overview

  • Supplier
    MedChem Express
  • Product Name
    ML417 [1386162-69-1]
  • Delivery Days Customer
    9
  • CAS Number
    1386162-69-1
  • Certification
    Research Use Only
  • Estimated Purity
    99.50
  • Molecular Formula
    C22H25N3O3
  • Molecular Weight
    379.45
  • Scientific Description
    ML417 is a selective and brain penetrant D3 dopamine receptor (D3R) agonist, with an EC50 of 38 nM. ML417 potently promotes D3R-mediated beta-arrestin translocation, G protein mediated signaling, and pERK phosphorylation with minimal effects on other GPCR-mediated signaling. ML417 exhibits neuroprotection against toxin-induced neurodegeneration of dopaminergic neurons[1].
  • SMILES
    O=C(C(N1)=CC2=C1C=CC=C2)N3CCN(CCOC4=CC=C(OC)C=C4)CC3
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

MSDS

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