ML67-33 [1443290-89-8]

MedChem Express

ML67-33 [1443290-89-8]

9

1443290-89-8

Research Use Only

99.28

C18H17Cl2N5

374.27

ML67-33 is a selective activator of temperature- and mechano-sensitive K2P channels. ML67-33 rapidly and reversibly affects K2P2.1 (TREK-1) with EC50s of 36.3 microM and 9.7 microM in cell-free and HEK293 cells, respectively[1].

CC1(C)C2=C(C=CC(Cl)=C2)N(CCC3=NN=NN3)C4=CC=C(Cl)C=C14

-20°C

12352200