ML753286

MedChem Express

ML753286 [1699720-89-2]

10

1699720-89-2

Research Use Only

C20H25N3O3

355.43

ML753286 is an orally active and selective BCRP (Breast cancer resistance protein) inhibitor with an IC 50 of 0.6 microM. ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions, and is stable in plasma cross species [1] .

COC1=CC=C2C(NC3=C2C[C@]4(N([C@H]3CC(C)C)C([C@@H](NC4=O)C)=O)[H])=C1

-20°C,2°C to 8°C

12352200