ML786 [1237586-97-8]
HY-14979
CAS Number1237586-97-8
Product group Chemicals
Molecular Weight538.56
Overview
- SupplierMedChem Express
- Product NameML786 [1237586-97-8]
- Delivery Days Customer9
- CAS Number1237586-97-8
- CertificationResearch Use Only
- Molecular FormulaC29H29F3N4O3
- Molecular Weight538.56
- Scientific DescriptionML786 is a potent and orally bioavailable Raf inhibitor, with IC50s of 2.1, 4.2, and 2.5 nM for V600EdeltaB-Raf, wt B-Raf, and C-Raf, respectively. ML786 also inhibits Abl-1, DDR2, EPHA2, KDR, and RET (IC50=[1].
- SMILESO=C(CC1)NC2=C1C(OC3=CC=C(CC[C@@H](NC(C4=CC(C(F)(F)F)=CC(C(C)(C)N)=C4)=O)C5)C5=C3)=CC=N2
- UNSPSC12131703