WB analysis of HEK293T (A), NIH3T3 (B), PC12 (C) whole cell lysates using GTX32300 MLK3 (phospho Thr277/Ser281) antibody.
WB analysis of HEK293T (A), NIH3T3 (B), PC12 (C) whole cell lysates using GTX32300 MLK3 (phospho Thr277/Ser281) antibody.
MLK3 (phospho Thr277/Ser281) antibody
GTX32300
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetMAP3K11
Overview
- SupplierGeneTex
- Product NameMLK3 (phospho Thr277/Ser281) antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID4296
- Target nameMAP3K11
- Target descriptionmitogen-activated protein kinase kinase kinase 11
- Target synonymsMEKK11; mitogen-activated protein kinase kinase kinase 11; mixed lineage kinase 3; MLK3; MLK-3; protein-tyrosine kinase PTK1; PTK1; SH3 domain-containing proline-rich kinase; SPRK; src-homology 3 domain-containing proline-rich kinase
- HostRabbit
- IsotypeIgG
- Modification TypePhosphorylated
- Protein IDQ16584
- Protein NameMitogen-activated protein kinase kinase kinase 11
- Scientific DescriptionThe protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq, Jul 2008]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203