MLKL antibody

GeneTex

MLKL antibody

9

WB: 1:1000. IHC-P: 1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

Mlkl

mixed lineage kinase domain-like

9130019I15Rik, mixed lineage kinase domain-like protein

Rabbit

IgG

Mixed lineage kinase domain-like protein

This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to lack protein kinase activity. This protein plays a critical role in tumor necrosis factor (TNF)-induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (Rip3), which is a key signaling molecule in necroptosis pathway. Knockout of this gene in mice showed that it is essential for necroptosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2015]

Human, Mouse

-20°C or -80°C,2°C to 8°C

12352203