
ELISA analysis of 0.2microg GTX52000 anitgen in 100microl buffer using serial diluted GTX52000 MLLT11 antibody.
MLLT11 antibody
GTX52000
Overview
- SupplierGeneTex
- Product NameMLLT11 antibody
- Delivery Days Customer9
- ApplicationsELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID10962
- Target nameMLLT11
- Target descriptionMLLT11 transcription factor 7 cofactor
- Target synonymsAF1Q; ALL1 fused gene from chromosome 1q; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11; myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11; protein AF1q
- HostRabbit
- IsotypeIgG
- Protein IDQ13015
- Protein NameProtein AF1q
- Scientific DescriptionThe gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203