MMAE-d8 [2070009-72-0]
T10948
CAS Number2070009-72-0
Product group Chemicals
Molecular Weight726.03
Overview
- SupplierTargetMol Chemicals
- Product NameMMAE-d8 [2070009-72-0]
- Delivery Days Customer19
- CAS Number2070009-72-0
- CertificationResearch Use Only
- Chemical NameMMAE-d8
- Molecular FormulaC39H59D8N5O7
- Molecular Weight726.03
- Scientific DescriptionD8-MMAE (D8-Monomethyl auristatin E) is an effective mitotic inhibitor and tubulin inhibitor, deuterated MMAE.
- Shelf life instruction3 years
- SMILES[2H]C([2H])([2H])C([2H])(C([2H])([2H])[2H])[C@]([2H])(NC(=O)[C@@H](NC)C(C)C)C(=O)N(C)[C@@H]([C@@H](C)CC)[C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1)OC
- Storage Instruction-20°C
- UNSPSC12352200
References
- Li F, Emmerton KK, Jonas M, et al. Intracellular Released Payload Influences Potency and Bystander-Killing Effects of Antibody-Drug Conjugates in Preclinical Models. Cancer Res. 2016,76(9):2710-9. doi: 10.1158/0008-5472.CAN-15-1795Read this paper
MSDS
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