MMAF (GMP)

MedChem Express

MMAF (GMP) [745017-94-1]

14

745017-94-1

Research Use Only

C39H65N5O8

731.96

MMAF (Monomethylauristatin F) GMP is a GMP grade MMAF (HY-15579). MMAF (Monomethylauristatin F) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF (Monomethylauristatin F) is widely used as a cytotoxic component of antibody-drug conjugates ( ADC s) such as vorsetuzumab mafodotin and SGN-CD19A [1] [2] [3] .

CC(C)[C@H](NC)C(N[C@H](C(N([C@@H]([C@@H](C)CC)[C@H](OC)CC(N1CCC[C@@]1([H])[C@H](OC)[C@@H](C)C(N[C@H](C(O)=O)CC2=CC=CC=C2)=O)=O)C)=O)C(C)C)=O

12352200