MMG-0358

AdipoGen Life Sciences

MMG-0358

10

1378976-02-3

Research Use Only

>98%

Warning

C8H6ClN3O

195.6

Chemical. CAS: 1378976-02-3. Formula: C8H6ClN3O. MW: 195.6. Potent triazole IDO1 (indoleamine 2,3-dioxygenase 1) inhibitor. Has IC50 values of 2nM in a cellular assay on mIDO1, 80nM in a cellular assay on hIDO1, 330nM in an enzymatic assay on hIDO1 at pH 6.5 and 71nM in an enzymatic assay on hIDO1 at pH 7.4. Shown to be active in vivo. - Potent triazole IDO1 (indoleamine 2,3-dioxygenase 1) inhibitor. Has IC50 values of 2nM in a cellular assay on mIDO1, 80nM in a cellular assay on hIDO1, 330nM in an enzymatic assay on hIDO1 at pH 6.5 and 71nM in an enzymatic assay on hIDO1 at pH 7.4. Shown to be active in vivo.

OC1=C(C=C(Cl)C=C1)C1=CN=NN1

-20°C,2°C to 8°C

12352200