MMG-11 [313254-94-3]

MedChem Express

MMG-11 [313254-94-3]

9

313254-94-3

Research Use Only

99.24

C15H14O7

306.27

MMG-11 is a potent and selective human TLR2 antagonist with low cytotoxicity. MMG-11 inhibits both TLR2/1 and TLR2/6 signaling with IC50s of 1.7 microM for Pam3CSK4-induced hTLR2/1 and 5.7 microM for Pam2CSK4-induced hTLR2/6 responses[1].

OC1=C(O)C(O)=C(C(CC2=CC=C(C(OCC)=O)O2)=O)C=C1

-20°C,2°C to 8°C

12352200