Bio-Connect

MMP24 antibody

GTX128246
GeneTex
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse
TargetMMP24
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Overview

  • Supplier
    GeneTex
  • Product Name
    MMP24 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID10893
  • Target name
    MMP24
  • Target description
    matrix metallopeptidase 24
  • Target synonyms
    matrix metallopeptidase 24 (membrane-inserted); matrix metalloproteinase 24 (membrane-inserted); matrix metalloproteinase-24; membrane-type 5 matrix metalloproteinase; membrane-type matrix metalloproteinase 5; MMP-24; MMP25; MT5MMP; MT5-MMP; MT-MMP 5; MTMMP5; MT-MMP5
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9Y5R2
  • Protein Name
    Matrix metalloproteinase-24
  • Scientific Description
    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasis. Nothdurft S et al., 2020 Nov 19, Oncogenesis
    Read more
  • A cellular complex of BACE1 and gamma-secretase sequentially generates Abeta from its full-length precursor. Liu L et al., 2019 Feb 4, J Cell Biol
    Read more