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MMP7 antibody [C2C3], C-term

GTX104658
GeneTex
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetMMP7
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Overview

  • Supplier
    GeneTex
  • Product Name
    MMP7 antibody [C2C3], C-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.45 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID4316
  • Target name
    MMP7
  • Target description
    matrix metallopeptidase 7
  • Target synonyms
    matrilysin; matrin; matrix metallopeptidase 7 (matrilysin, uterine); matrix metalloproteinase 7 (matrilysin, uterine); matrix metalloproteinase-7; MMP-7; MPSL1; PUMP-1; pump-1 protease; uterine matrilysin; uterine metalloproteinase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP09237
  • Protein Name
    Matrilysin
  • Scientific Description
    Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Piperine Provides Neuroprotection against Kainic Acid-Induced Neurotoxicity via Maintaining NGF Signalling Pathway. Hsieh TY et al., 2022 Apr 20, Molecules
    Read more
  • MRPS31 loss is a key driver of mitochondrial deregulation and hepatocellular carcinoma aggressiveness. Min S et al., 2021 Nov 12, Cell Death Dis
    Read more
  • Klotho retards renal fibrosis through targeting mitochondrial dysfunction and cellular senescence in renal tubular cells. Miao J et al., 2021 Jan, Physiol Rep
    Read more
  • Early activation of fibroblasts is required for kidney repair and regeneration after injury. Zhou D et al., 2019 Nov, FASEB J
    Read more
  • MMP7 cleaves remyelination-impairing fibronectin aggregates and its expression is reduced in chronic multiple sclerosis lesions. Wang P et al., 2018 Aug, Glia
    Read more
  • The role of kinesin KIF18A in the invasion and metastasis of hepatocellular carcinoma. Luo W et al., 2018 Feb 21, World J Surg Oncol
    Read more
  • Wnt9a Promotes Renal Fibrosis by Accelerating Cellular Senescence in Tubular Epithelial Cells. Luo C et al., 2018 Apr, J Am Soc Nephrol
    Read more
  • FHL2 promotes tubular epithelial-to-mesenchymal transition through modulating beta-catenin signalling. Cai T et al., 2018 Mar, J Cell Mol Med
    Read more
  • TOP2A induces malignant character of pancreatic cancer through activating beta-catenin signaling pathway. Pei YF et al., 2018 Jan, Biochim Biophys Acta Mol Basis Dis
    Read more
  • C-X-C Chemokine Receptor Type 4 Plays a Crucial Role in Mediating Oxidative Stress-Induced Podocyte Injury. Mo H et al., 2017 Aug 20, Antioxid Redox Signal
    Read more

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