MMP7 antibody [C2C3], C-term
GTX104658
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Human, Mouse, Rat
TargetMMP7
Overview
- SupplierGeneTex
- Product NameMMP7 antibody [C2C3], C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.45 mg/ml
- ConjugateUnconjugated
- Gene ID4316
- Target nameMMP7
- Target descriptionmatrix metallopeptidase 7
- Target synonymsmatrilysin; matrin; matrix metallopeptidase 7 (matrilysin, uterine); matrix metalloproteinase 7 (matrilysin, uterine); matrix metalloproteinase-7; MMP-7; MPSL1; PUMP-1; pump-1 protease; uterine matrilysin; uterine metalloproteinase
- HostRabbit
- IsotypeIgG
- Protein IDP09237
- Protein NameMatrilysin
- Scientific DescriptionProteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq]
- ReactivityBovine, Human, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Piperine Provides Neuroprotection against Kainic Acid-Induced Neurotoxicity via Maintaining NGF Signalling Pathway. Hsieh TY et al., 2022 Apr 20, MoleculesRead more
- MRPS31 loss is a key driver of mitochondrial deregulation and hepatocellular carcinoma aggressiveness. Min S et al., 2021 Nov 12, Cell Death DisRead more
- Klotho retards renal fibrosis through targeting mitochondrial dysfunction and cellular senescence in renal tubular cells. Miao J et al., 2021 Jan, Physiol RepRead more
- Early activation of fibroblasts is required for kidney repair and regeneration after injury. Zhou D et al., 2019 Nov, FASEB JRead more
- MMP7 cleaves remyelination-impairing fibronectin aggregates and its expression is reduced in chronic multiple sclerosis lesions. Wang P et al., 2018 Aug, GliaRead more
- The role of kinesin KIF18A in the invasion and metastasis of hepatocellular carcinoma. Luo W et al., 2018 Feb 21, World J Surg OncolRead more
- Wnt9a Promotes Renal Fibrosis by Accelerating Cellular Senescence in Tubular Epithelial Cells. Luo C et al., 2018 Apr, J Am Soc NephrolRead more
- FHL2 promotes tubular epithelial-to-mesenchymal transition through modulating beta-catenin signalling. Cai T et al., 2018 Mar, J Cell Mol MedRead more
- TOP2A induces malignant character of pancreatic cancer through activating beta-catenin signaling pathway. Pei YF et al., 2018 Jan, Biochim Biophys Acta Mol Basis DisRead more
- C-X-C Chemokine Receptor Type 4 Plays a Crucial Role in Mediating Oxidative Stress-Induced Podocyte Injury. Mo H et al., 2017 Aug 20, Antioxid Redox SignalRead more