MMSET-IN-1 [1998139-29-9]

MedChem Express

MMSET-IN-1 [1998139-29-9]

10

1998139-29-9

Research Use Only

C18H29N7O5

423.47

MMSET-IN-1 is a multiple myeloma SET domain (MMSET, aka NSD2/WHSC1) inhibitor against SETD2 and MMSET with IC50s of 0.49 and 3.3 microM, respectively. MMSET-IN-1 has a Kd of 1.6 microM for MMSET[1].

O=C(O)[C@@H](N)CCC(NCCC)C[C@H]1O[C@@H](N2C=NC3=C(N)N=CN=C23)[C@H](O)[C@@H]1O

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