MMV390048

MedChem Express

MMV390048 [1314883-11-8]

10

1314883-11-8

Research Use Only

99.17

C18H14F3N3O2S

393.38

MMV390048 is a representative of a new chemical class of Plasmodium PI4K inhibitor (K d app =0.3 microM). MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. falciparum and human kinases apart from human PIP4K2C, thus alleviating potential kinase-mediated safety concerns. MMV390048 is an antimalarial agent [1] .

NC1=NC=C(C2=CC=C(S(=O)(C)=O)C=C2)C=C1C3=CC=C(C(F)(F)F)N=C3

2°C to 8°C

12352200