MNDA Antibody

Cusabio

MNDA Antibody

20

Western Blot, ELISA

Research Use Only

Polyclonal

Unconjugated

MNDA

myeloid cell nuclear differentiation antigen

epididymis secretory sperm binding protein; myeloid cell nuclear differentiation antigen; PYHIN3

Rabbit

IgG

Myeloid cell nuclear differentiation antigen

The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons. Briggs J.A., J. Cell. Biochem. 49:82-92(1992). The MGC Project Team; Genome Res. 14:2121-2127(2004). Burrus G.R., J. Cell. Biochem. 48:190-202(1992).

Human

-20°C or -80°C

12352203