MNK1/2-IN-7 [2548283-27-6]

TargetMol Chemicals

MNK1/2-IN-7 [2548283-27-6]

16

Research Use Only

C31H31N5O2

505.61

MNK1/2-IN-7 (compound 20j) serves as an orally administered inhibitor targeting MNK1/2, known for its anticancer properties and hERG safety. It also blocks the phosphorylation of eIF4E, thereby disrupting the MNK/eIF4E signaling pathway and reducing cancer cell growth. Additionally, MNK1/2-IN-7 synergizes effectively with Ibrutinib. [15] [1]

C(=O)(C1=CC=C(C2=NN3C(=CN=C3C=C2)C4=CC=5C(O4)=CC=CC5)C=C1)N6CCC(CC6)N7CCCCC7

-20°C

51202000