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ProductsBack/Molecular Glue/PROTAC(r) Optimization Kit for CDK/Cyclin K-DDB1 Containing Complex
Molecular Glue-mediated interaction of CDK12 /Cyclin K and DDB1/Cereblon Complex.
Molecular Glue-mediated interaction of CDK12 /Cyclin K and DDB1/Cereblon Complex.
Molecular Glue-mediated interaction of CDK12 /Cyclin K and DDB1/Cereblon Complex.

Molecular Glue/PROTAC(r) Optimization Kit for CDK/Cyclin K-DDB1 Containing Complex

Research Use Only
82588
BPS Bioscience
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Overview

  • Supplier
    BPS Bioscience
  • Product Name
    Molecular Glue/PROTAC(r) Optimization Kit for CDK/Cyclin K-DDB1 Containing Complex
  • Delivery Days Customer
    7
  • Certification
    Research Use Only
  • Scientific Description
    The Molecular Glue/PROTAC® Optimization Kit for CDK/Cyclin K-DDB1 Containing Complex is an AlphaLISA® assay designed for the testing and profiling of Molecular Glues (MG) and PROTACs targeting CDK12 (cyclin dependent kinase 12) or CDK13 kinases and any complex containing DDB1 (DNA damage binding protein 1). The kit comes with enough recombinant CDK12/Cyclin K complex, Cereblon/DDB1/CUL4A (culin 4A)/Rbx1 (RING-box protein 1) as a DDB1-containing complex, and optimized PROTAC® buffer. This kit also contains the control molecular glue (R)-CR8, and the dual CDK12-CDK13 inhibitor THZ531.
  • UNSPSC
    41116133