Molidustat

MedChem Express

Molidustat [1154028-82-6]

10

1154028-82-6

Research Use Only

98.75

C13H14N8O2

314.30

Molidustat (BAY 85-3934) is an orally active inhibitor of hypoxia-inducible factor prolyl hydroxylase ( HIF-PH ) with IC 50 values of 480 nM, 280 nM, and 450 nM for PHD1 , PHD2 , and PHD3 , respectively. Molidustat can elevate the levels of circulating erythropoietin (EPO) to near-normal physiological ranges. Molidustat can be utilized in the research of renal anemia [1] [2] .

O=C1C(N2N=NC=C2)=CNN1C3=NC=NC(N4CCOCC4)=C3

-20°C,2°C to 8°C

12352200