Mollugin [55481-88-4]

MedChem Express

Mollugin [55481-88-4]

9

55481-88-4

Research Use Only

99.48

C17H16O4

284.31

Mollugin is an orally active and potent NF-kappaB inhibitor. Mollugin induces S-phase arrest of HepG2 cells, and increased intracellular reactive oxygen species (ROS) levels. Mollugin induces DNA damage in HepG2 cells, as well as an increase in the expression of p-H2AX. Mollugin shows anti-cancer effect by inhibiting TNF-alpha-induced NF-kappaB activation. Mollugin enhances the osteogenic action of BMP-2 (bone morphogenetic protein 2) via the p38-Smad signaling pathway[1][2][3].

O=C(C1=C(C=CC(C)(C)O2)C2=C3C=CC=CC3=C1O)OC

2°C to 8°C

12352200