Chemical Structure
Chemical Structure
Momelotinib [1056634-68-4]
SYN-1035
CAS Number1056634-68-4
Product group Chemicals
Estimated Purity>95%
Molecular Weight414.5
Overview
- SupplierSYNkinase
- Product NameMomelotinib [1056634-68-4]
- Delivery Days Customer10
- CAS Number1056634-68-4
- CertificationResearch Use Only
- Estimated Purity>95%
- Molecular FormulaC23H22N6O2
- Molecular Weight414.5
- Scientific DescriptionChemical. CAS: 1056634-68-4. Formula: C23H22N6O2. MW: 414.5. CYT387 is selective inhibitor of JAK1 and JAK2 kinases including the JAK2V617F mutant . Using ATP kinase assays IC(50) values for JAK1 (11nm), JAK2, (18nM), JAK2, JAK2V617F (23nM) JAK3 (155nM), and TYK2 (17nM). In testing kinase arrays, CYT387 also had activity (defined as an IC(50) < 100nM) detected against CDK2/cyclin A, MAPK8 (JNK1), PRKCN (PKD3), PRKD1 (PKCmicro), ROCK2, and TBK1 kinase as well. - CYT387 is selective inhibitor of JAK1 and JAK2 kinases including the JAK2V617F mutant . Using ATP kinase assays IC(50) values for JAK1 (11nm), JAK2, (18nM), JAK2, JAK2V617F (23nM) JAK3 (155nM), and TYK2 (17nM). In testing kinase arrays, CYT387 also had activity (defined as an IC(50) < 100nM) detected against CDK2/cyclin A, MAPK8 (JNK1), PRKCN (PKD3), PRKD1 (PKCmicro), ROCK2, and TBK1 kinase as well.
- Storage Instruction2°C to 8°C
- UNSPSC51202000
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![Momelotinib [1056634-68-4]](https://www.targetmol.com/group3/M00/35/45/CgoaEGayGm6ETFKhAAAAAL8pUNY007.png)
Product group Chemicals
CAS Number1056634-68-4
Estimated Purity98.75%
Molecular Weight414.46
- SizePrice