Momelotinib (dihydrochloride) [1380317-28-1]
HY-W064657
CAS Number1380317-28-1
Product group Chemicals
Molecular Weight487.38
Overview
- SupplierMedChem Express
- Product NameMomelotinib (dihydrochloride) [1380317-28-1]
- Delivery Days Customer9
- CAS Number1380317-28-1
- CertificationResearch Use Only
- Molecular FormulaC23H24Cl2N6O2
- Molecular Weight487.38
- Scientific DescriptionMomelotinib (dihydrochloride) is a JAK1/JAK2 inhibitor that also antagonizes ACVR1, leading to downregulation of Hepcidin expression and increased availability of iron for erythropoiesis. Momelotinib (dihydrochloride) can reduce transfusion burden and spleen enlargement caused by myelofibrosis, showing potential value in research and application within the field of myelofibrosis[1].
- SMILESO=C(NCC#N)C(C=C1)=CC=C1C2=NC(NC(C=C3)=CC=C3N4CCOCC4)=NC=C2.Cl.Cl
- UNSPSC12352200
