Monascuspiloin [1011244-19-1]
HY-N12124
CAS Number1011244-19-1
Product group Chemicals
Molecular Weight360.44
Overview
- SupplierMedChem Express
- Product NameMonascuspiloin [1011244-19-1]
- Delivery Days Customer9
- CAS Number1011244-19-1
- CertificationResearch Use Only
- Molecular FormulaC21H28O5
- Molecular Weight360.44
- Scientific DescriptionMonascuspiloin (Monascinol) exhibits anti-androgenic activity with an IC50 of 7 microM. Monascuspiloin inhibits viability of PC-3 and LNCaP with IC50 of 45 and 47 microM. Monascuspiloin induces apoptosis in LNCaP through inhibition of Akt/mTOR signaling pathway, induces autophagy through activation AMPK signaling pathway and arrest cell cycle at G2/M phase in PC-3. Monascuspiloin exhibits antitumor efficacy in mice[1][2].
- SMILESC[C@]12[C@@](CC3=C(COC(/C=C/C)=C3)C2=O)([H])[C@H](C(O1)=O)[C@@H](O)CCCCC
- UNSPSC12352200