Monobenzone

MedChem Express

Monobenzone [103-16-2]

10

103-16-2

Research Use Only

99.98

C13H12O2

200.237

Monobenzone is a potent skin depigmenting agent. Monobenzone induces depigmentation and exhibits good potential for vitiligo research. Monobenzone is a potent inhibitor of RNR (Ribonucleotide reductase) enzyme activity by targeting RRM2 (a regulatory small subunit M2 of RNR) protein, and thus has significant anti-leukemia efficacy in vitro and in vivo. Monobenzone inhibits acute myeloid leukemia (AML) cells proliferation and DNA synthesis, induces cell cycle arrest, and Apoptosis [1][2].

OC1=CC=C(C=C1)OCC2=CC=CC=C2

-20°C,2°C to 8°C

12352200