Monomethyl auristatin E intermediate-2

MedChem Express

Monomethyl auristatin E intermediate-2

14

Research Use Only

97.54

C15H27NO6

317.38

Monomethyl auristatin E intermediate-2 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].

OC([C@H](C)[C@@H](OCOC)[C@H]1N(C(OC(C)(C)C)=O)CCC1)=O

2°C to 8°C

41115800