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Monomethyl auristatin E intermediate-4 [1823777-46-3]

HY-43147
MedChem Express
CAS Number1823777-46-3
Product group Chemicals
Molecular Weight363.45
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Monomethyl auristatin E intermediate-4 [1823777-46-3]
  • Delivery Days Customer
    14
  • CAS Number
    1823777-46-3
  • Certification
    Research Use Only
  • Molecular Formula
    C20H29NO5
  • Molecular Weight
    363.45
  • Scientific Description
    Monomethyl auristatin E intermediate-4 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
  • SMILES
    CCC(C)C(NC(OCC1=CC=CC=C1)=O)C(CC(OC(C)(C)C)=O)=O
  • UNSPSC
    12352200