Monomethyl auristatin E intermediate-6 [135383-54-9]
HY-78899
CAS Number135383-54-9
Product group Chemicals
Molecular Weight363.45
Overview
- SupplierMedChem Express
- Product NameMonomethyl auristatin E intermediate-6 [135383-54-9]
- Delivery Days Customer14
- CAS Number135383-54-9
- CertificationResearch Use Only
- Molecular FormulaC20H29NO5
- Molecular Weight363.45
- Scientific DescriptionMonomethyl auristatin E intermediate-6 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
- SMILESCC[C@H](C)[C@H](NC(OCC1=CC=CC=C1)=O)C(CC(OC(C)(C)C)=O)=O
- UNSPSC12352200