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Monomethyl auristatin E intermediate-7 [135383-55-0]

HY-78901
MedChem Express
CAS Number135383-55-0
Product group Chemicals
Estimated Purity99.54
Molecular Weight365.46
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Monomethyl auristatin E intermediate-7 [135383-55-0]
  • Delivery Days Customer
    14
  • CAS Number
    135383-55-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.54
  • Molecular Formula
    C20H31NO5
  • Molecular Weight
    365.46
  • Scientific Description
    Monomethyl auristatin E intermediate-7 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
  • SMILES
    CC[C@H](C)[C@@H]([C@@H](CC(OC(C)(C)C)=O)O)NC(OCC1=CC=CC=C1)=O
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200