Motesanib Diphosphate

AbMole BioScience

Motesanib Diphosphate

9

857876-30-3

Research Use Only

>98%

C22H23N5O.2H3PO4

569.44

Motesanib (AMG 706) is a potent ATP-competitive inhibitor of VEGFR1/2/3, PDGFR, c-Kit and Ret with IC50 of 2 nM, 3 nM, 6 nM, 84 nM, 8 nM and 59 nM, respectively.

CC1(C)CNC2=CC(=CC=C12)NC(=O)C3=C(NCC4=CC=NC=C4)N=CC=C3.O[P](O)(O)=O.O[P](O)(O)=O

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