Mouse anti Cytokeratin 16 / Keratin K16

Nordic-MUbio

Mouse anti Cytokeratin 16 / Keratin K16

7

Keratin 16 is specifically found in hyperprolifeRative squamous epithelium such as psoriatic lesions and squamous cell carcinomas, e.g. of the lung. It is expressed in suprabasal Keratinocytes of wounded epidermis, a situation of high cell turnover. LL025

LL025 is suitable for immunoblotting (Western blot) and for immunohistochemistry on frozen tissue and paraffin embedded material. Optimal antibody dilution should be determined by titration; 1:25 - 1:50 for immunohistochemistry with avidin-biotinylated Horseradish peroxidase complex (ABC) as detection reagent. For use in paraffin embedded tissue sections high pressure retrieval at pH 8,0 is recommended.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Immunohistochemistry (frozen);Immunohistochemistry (paraffin);Western Blotting

Primary antibodies

Research Use Only

Monoclonal

LL025

KRT16

keratin 16

CK16; cytokeratin 16; FNEPPK; focal non-epidermolytic palmoplantar keratoderma; K16; K1CP; keratin 16, type I; keratin, type I cytoskeletal 16; KRT16A; NEPPK; PC1

Mouse

IgG1

Keratin, type I cytoskeletal 16

LL025 is a Mouse monoclonal IgG1 antibody derived by fusion of SP2/0-Ag14 murine myeloma cells with spleen cells from a Mouse immunized with a synthetic peptide corresponding to an amino acid sequence of the carboxyl terminus of Human Keratin 16.

Human

Human

12352203