Bio-Connect

Mouse anti Human Caspase-8

Research Use Only
X1175M
Nordic-MUbio
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetCASP8
Price on request
100 ug
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Nordic-MUbio
  • Product Name
    Mouse anti Human Caspase-8
  • Delivery Days Customer
    7
  • Application Supplier Note
    Detects proenzyme form of human Caspase-8 by Western blot analysis as well as one of the cleavage products. Optimal concentration should be evaluated by serial dilutions.
  • Applications
    Western Blot
  • Applications Supplier
    Western Blotting;Western Blotting
  • Category Supplier
    Primary antibodies
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    FLICE 1 1-37
  • Conjugate
    Unconjugated
  • Gene ID841
  • Target name
    CASP8
  • Target description
    caspase 8
  • Target synonyms
    ALPS2B; apoptotic cysteine protease; apoptotic protease Mch-5; CAP4; Casp-8; caspase 8, apoptosis-related cysteine peptidase; caspase 8, apoptosis-related cysteine protease; caspase-8; FADD-homologous ICE/CED-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MACH; MACH-alpha-1/2/3 protein; MACH-beta-1/2/3/4 protein; MCH5; MORT1-associated ced-3 homolog
  • Host
    Mouse
  • Isotype
    IgG
  • Protein IDQ14790
  • Protein Name
    Caspase-8
  • Scientific Description
    Cysteine-requiring Aspartate Protease-8; Apoptotic protease Mch-5; ICE-like apoptotic protease 5; FADD-like ICE
  • Shelf life instruction
    See expiration date on vial
  • Reactivity
    Human
  • Reactivity Supplier
    Human
  • Reactivity Supplier Note
    Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant human capase-8 protein and mouse myeloma cells.
  • UNSPSC
    12352203

References

  • 1. Cohen, G.M., et al. Caspases: the executioners of apoptosis. Biochem. J. 1997, 326, 1-16 2. Martin, D.A., et al. Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHalpha1) death signal. J. Biol. Chem. 1998, 273, 4345-4349 3. Green, D.R., Apoptotic pathways: the roads to ruin. Cell 1998, 94, 695-698 4. Hu, S., et al. I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis. J. Biol. Chem. 1997, 272, 17255-17257