Mouse anti Human Caspase-8
X1175M
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetCASP8
Overview
- SupplierNordic-MUbio
- Product NameMouse anti Human Caspase-8
- Delivery Days Customer7
- Application Supplier NoteDetects proenzyme form of human Caspase-8 by Western blot analysis as well as one of the cleavage products. Optimal concentration should be evaluated by serial dilutions.
- ApplicationsWestern Blot
- Applications SupplierWestern Blotting;Western Blotting
- Category SupplierPrimary antibodies
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDFLICE 1 1-37
- ConjugateUnconjugated
- Gene ID841
- Target nameCASP8
- Target descriptioncaspase 8
- Target synonymsALPS2B; apoptotic cysteine protease; apoptotic protease Mch-5; CAP4; Casp-8; caspase 8, apoptosis-related cysteine peptidase; caspase 8, apoptosis-related cysteine protease; caspase-8; FADD-homologous ICE/CED-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MACH; MACH-alpha-1/2/3 protein; MACH-beta-1/2/3/4 protein; MCH5; MORT1-associated ced-3 homolog
- HostMouse
- IsotypeIgG
- Protein IDQ14790
- Protein NameCaspase-8
- Scientific DescriptionCysteine-requiring Aspartate Protease-8; Apoptotic protease Mch-5; ICE-like apoptotic protease 5; FADD-like ICE
- Shelf life instructionSee expiration date on vial
- ReactivityHuman
- Reactivity SupplierHuman
- Reactivity Supplier NoteHybridoma produced by the fusion of splenocytes from mice immunized with recombinant human capase-8 protein and mouse myeloma cells.
- UNSPSC12352203
References
- 1. Cohen, G.M., et al. Caspases: the executioners of apoptosis. Biochem. J. 1997, 326, 1-16 2. Martin, D.A., et al. Membrane oligomerization and cleavage activates the caspase-8 (FLICE/MACHalpha1) death signal. J. Biol. Chem. 1998, 273, 4345-4349 3. Green, D.R., Apoptotic pathways: the roads to ruin. Cell 1998, 94, 695-698 4. Hu, S., et al. I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis. J. Biol. Chem. 1997, 272, 17255-17257