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Mouse anti Human Cytochrome P450 3A5

Research Use Only
X2047M
Nordic-MUbio
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCYP3A5
Price on request
200 ug
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Overview

  • Supplier
    Nordic-MUbio
  • Product Name
    Mouse anti Human Cytochrome P450 3A5
  • Delivery Days Customer
    7
  • Application Supplier Note
    Antibody can be used for Western blotting (1-2 microg/ml) and immunohistochemistry on formalin-fixed, paraffin-embedded tissues (1-5 microg/ml). When used in conjunction with CYP3A7 (Cat. No. X2048M), can differentiate between the CYP3A family members, 3A5 and 3A7. Optimal concentration should be evaluated by serial dilutions.
  • Applications
    Western Blot, ELISA, ImmunoHistoChemistry
  • Applications Supplier
    Western Blotting;ELISA;Western Blotting;Immunohistochemistry
  • Category Supplier
    Primary antibodies
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    F18 P3 B6
  • Conjugate
    Unconjugated
  • Gene ID1577
  • Target name
    CYP3A5
  • Target description
    cytochrome P450 family 3 subfamily A member 5
  • Target synonyms
    aryl hydrocarbon hydroxylase; CP35; CYPIIIA5; cytochrome P450 3A5; cytochrome P450 HLp2; cytochrome P450, family 3, subfamily A, polypeptide 5; cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5; cytochrome P450-PCN3; flavoprotein-linked monooxygenase; microsomal monooxygenase; P450PCN3; PCN3; xenobiotic monooxygenase
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP20815
  • Protein Name
    Cytochrome P450 3A5
  • Scientific Description
    CYP3A5; CYP450 3A5 (EC 1.14.14.1), Niphedipine oxidase, CYPIIIA5, P450-PCN3, HLp2
  • Shelf life instruction
    See expiration date on vial
  • Reactivity
    Human
  • Reactivity Supplier
    Human
  • Reactivity Supplier Note
    Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the C-terminus of the human CYP3A5 protein and mouse myeloma Ag8563 cells.
  • UNSPSC
    12352203

References

  • 1. Kumarakasingham, M., et al. (2005). Cytochrome p450 profile of colorectal cancer: Identification of markers of prognosis. Clin. Cancer Res. 11(10);3758-3765. 2. McCune, J.S., et al (2005). Contribution of CYP3A5 to hepatic and renal ifosfamide N-dechloroethlation. Drug Metab. Dispos. 33(7);1074-1081. 3. Kim, K.A., et al. (2007). Effect of polymorphic CYP3A5 genotype on the single-dose simvastatin pharmacokinetics in healthy subjects. J. Cin. Pharmacol. 47(1);87-93