Mouse Anti-Human Lambda Light Chain Secondary Antibody (clone ICO-106)

LifeSpan BioSciences

Mouse Anti-Human Lambda Light Chain Secondary Antibody (clone ICO-106)

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This antibody is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant. ELISA: Order BSA-free format for coating.. ELISA, Flo (0.5 - 1 µg/10E6 cells), IF (1 - 2 µg/ml), IHC, IHC-P (0.5 - 1 µg/ml), IP, WB (0.5 - 1 µg/ml) This antibody is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. In general the ratio of Kappa to Lambda is 3:1. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant. ELISA: Order BSA-free format for coating.

Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Monoclonal

ICO-106

0.2 mg/ml

Unconjugated

...

Mouse

IgG1

Human

2°C to 8°C

41116161