Mouse C Peptide ELISA Kit

Arigo Biolaboratories

Mouse C Peptide ELISA Kit

23

ELISA

Dynamic Range: 0.1 - 6.4 ng/ml

CV: < 10%

0.1 ng/ml

Cross-Reactivity:Mouse C Peptide I and II: 100%Rat C Peptide I: 80%Rat C Peptide II: 120%Human C Peptide: Not detected

~ 2.5 hours

Research Use Only

After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5 region and with the IGF2 gene at the 3 region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

2°C to 8°C

41116133