Mouse CD127 / IL7R ELISA Kit

Arigo Biolaboratories

Mouse CD127 / IL7R ELISA Kit

23

ELISA

Intra-Assay CV: 5.6%; Inter-Assay CV: 6.7%

15.6 pg/ml

There is no detectable cross-reactivity with other relevant proteins.

~ 5 hours

Research Use Only

The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2014]

2°C to 8°C

41116133