Mouse CD16 recombinant protein (His-tagged)

Arigo Biolaboratories

Mouse CD16 recombinant protein (His-tagged)

23

Other Application

Research Use Only

>95%

CD16, also known as Fc gamma receptor III (FcgammaRIII), is a transmembrane protein primarily found on the surface of natural killer (NK) cells, macrophages, and a subset of T cells. It plays a critical role in mediating antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis. CD16 binds to the Fc portion of immunoglobulin G (IgG) antibodies, facilitating the recognition and destruction of target cells or pathogens coated with antibodies. This interaction activates downstream signaling pathways, triggering cytotoxic responses. CD16s involvement in immune surveillance and host defense highlights its significance in immune regulation and therapeutic strategies targeting ADCC.

-20°C

41116100

Mouse