Mouse CD178 / Fas Ligand recombinant protein (Active) (His-tagged, N-ter)

Arigo Biolaboratories

Mouse CD178 / Fas Ligand recombinant protein (Active) (His-tagged, N-ter)

23

Other Application

Research Use Only

>98%

FASLG

Fas ligand

ALPS1B, APT1LG1, APTL, CD178, CD95-L, CD95L, FASL, TNFSF6, TNLG1A, tumor necrosis factor ligand superfamily member 6, CD95 ligand, Fas ligand (TNF superfamily, member 6), apoptosis (APO-1) antigen ligand 1, apoptosis antigen ligand, fas antigen ligand, mutant tumor necrosis factor family member 6, tumor necrosis factor ligand 1A

Tumor necrosis factor ligand superfamily member 6

This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.

-20°C

41116120

Human, Mouse