Mouse CD86 recombinant protein (Fc-tagged, C-ter)

Arigo Biolaboratories

Mouse CD86 recombinant protein (Fc-tagged, C-ter)

23

Binding activity test: Measured by its binding ability in a functional ELISA. Immobilized Recombinant Mouse CD86 at 2 microg/ml (100 microl/well) can bind Recombinant Human CTLA-4 with a linear range of 18-72 ng/ml.

Other Application

Research Use Only

>97%

Cd86

CD86 antigen

B7, B7-2, B7.2, B70, CLS1, Cd28l2, ETC-1, Ly-58, Ly58, MB7, MB7-2, TS/A-2, T-lymphocyte activation antigen CD86, activation B7-2 antigen, early T cell costimulatory molecule-1

T-lymphocyte activation antigen CD86

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, May 2011]

-20°C

41116100

Mouse