Mouse CHIT1 ELISA Kit

Arigo Biolaboratories

Mouse CHIT1 ELISA Kit

23

ELISA

Intra-Assay CV: 5.3%Inter-Assay CV: 7.1%

156 pg/ml

~ 5 hours

Research Use Only

Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2012]

2°C to 8°C

41116133