Bio-Connect

Mouse DEFB103A / BD-3 Protein (Native)

Research Use Only
LS-G133838
LifeSpan BioSciences
Product group Proteins / Signaling Molecules
Price on request
Packing Size
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Overview

  • Supplier
    LifeSpan BioSciences
  • Product Name
    Mouse DEFB103A / BD-3 Protein (Native)
  • Delivery Days Customer
    14
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Scientific Description
    Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The a-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, six human beta-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant Murine BD-3 is a 4.6 kDa protein containing 41 amino acid residues.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352202