Mouse IGFBP2 Protein (IGF-MM102)

KACTUS

Mouse IGFBP2 Protein (IGF-MM102)

9

Research Use Only

>95%

Insulin-like growth factor-binding protein 2

Insulin-like growth factor (IGF) binding protein 2 (IGFBP2) was discovered and identified as an IGF system regulator, controlling the distribution, function, and activity of IGFs in the pericellular space. IGFBP2 is a developmentally regulated gene that is highly expressed in embryonic and fetal tissues and markedly decreases after birth.IGFBP2 is upregulated and promotes several key oncogenic processes, such as epithelial-to-mesenchymal transition, cellular migration, invasion, angiogenesis, stemness, transcriptional activation, and epigenetic programming via signaling that is often independent of IGFs.

-20°C or -80°C,-80°C

12352202