Mouse IgG2a Fc, Tag Free on SDS-PAGE under reducing (R) and under non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%.
Mouse IgG2a Fc Protein, Tag Free (MALS verified)
IGA-M5207
Product group Proteins / Signaling Molecules
Overview
- SupplierACRObiosystems
- Product NameMouse IgG2a Fc Protein, Tag Free (MALS verified)
- Delivery Days Customer4
- Category SupplierOther Recombinant Proteins
- CertificationResearch Use Only
- Estimated Purity90%
- FormatPowder
- Scientific DescriptionCharacteristics: This protein carries no "tag". The protein has a calculated MW of 26.4 kDa. As a result of glycosylation, the protein migrates as 30-35 kDa under reducing (R) condition, and 55-60 kDa under non-reducing (NR) condition (SDS-PAGE). Description: Immunoglobulin G2 (IgG2) is a member of many immunoglobulin G developed and secreted by effective B cells. In wake of cutting by pepsin, IgG is divided into two F(ab)s with one antigen binding site and a high conserved Fc segment. The Fc segment bears a highly conserved N-glycosylation site. There are two members of IgG2: IgG2a and IgG2b. It was found that IgG2a was superior to IgG1 in activating complement. The glycosylation of the circulating immunoglobulin-γ (IgG) antibody molecules changes in rheumatoid arthritis.
- Shelf life instruction● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
- SourceMouse IgG2a Fc, Tag Free (IGA-M5207) is expressed from human 293 cells (HEK293). It contains AA Glu 98 - Lys 330 (Accession # CAC20702).
- Storage Instruction-20℃
- UNSPSC12352202