Mouse IL1RA recombinant protein (Active) (His-tagged, C-ter)

Arigo Biolaboratories

Mouse IL1RA recombinant protein (Active) (His-tagged, C-ter)

23

Other Application

Research Use Only

>98%

Il1rn

interleukin 1 receptor antagonist

F630041P17Rik, IL-1ra, interleukin-1 receptor antagonist protein, IL-1RN, IL1 inhibitor, IRAP

Interleukin-1 receptor antagonist protein

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

-20°C

41116120

Mouse