Mouse Interferon gamma protein, His tag (active)

GeneTex

Mouse Interferon gamma protein (active)

9

IFN-gamma is an important activator of macrophages, it promotes production of inducible Nitric Oxide Synthase (iNOS) in macrophages. After stimulated with IFN-gamma, morphological changes will occur in murine macrophage cell line (Raw 246. 7 cells), and inducible nitric-oxide synthase (iNOS) in the cells will increase. Raw 246. 7 cells were incubated in DMEM with IFN-gamma (2 ng/ml) for 24h, then cells were observed by inverted microscope.

Functional Assay

Research Use Only

Unconjugated

Interferon gamma

This gene encodes a soluble cytokine that is a member of the type II interferon class. The encoded protein is secreted by cells of both the innate and adaptive immune systems. The active protein is a homodimer that binds to the interferon gamma receptor which triggers a cellular response to viral and microbial infections. Mice deficient in this gene have increased susceptibility to viral, bacterial and parasitic infections and to several autoimmune diseases. [provided by RefSeq, Dec 2015]

-20°C or -80°C,2°C to 8°C

12352202