Mouse MMP9 Assay Kit

Arigo Biolaboratories

Mouse MMP9 Assay Kit

23

Functional Assay

4 - 4000 pg/ml

20 pg/ml for 1 hour incubation1 pg/ml for 6 hours incubation

Measures endogenous active MMP9 (naturally occurring) or total active MMP9 (following activation with APMA).

Overnight

Research Use Only

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMPs are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq, Jul 2008]

-20°C

41116133