Anti-ARAP1 Purified

EXBIO

Anti-ARAP1 Purified

7

Western blotting: Recommended dilution: 2 microg/ml

ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry

Research Use Only

ARAP1-2

1 mg/ml

IgG1

ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAP and RhoGAP activities, containing five PH domains and ankyrin repeate. This adaptor seems to serve as a link between phosphoinositide- Arf-, and Rho-mediated cell signaling. ARAP1 supports the plasma membrane recycling of angiotensin II type 1 receptor (AT1) and is important also for cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4) to the plasma membrane, thus promoting the TRAIL-induced apoptosis in certain cell types. ARAP1 also affects cell spreading.

Human

2°C to 8°C

12352203