Anti-Hu BCL2 Purified
11-668
ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
Overview
- SupplierEXBIO
- Product NameAnti-Hu BCL2 Purified
- Delivery Days Customer7
- Application Supplier NoteFlow cytometry: Recommended dilution: 1-5 microg/ml. Intracellular staining. Western blotting: Recommended dilution: 1-2 microg/ml.
- ApplicationsFlow Cytometry, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- Clone IDBcl-2/100
- Concentration1 mg/ml
- IsotypeIgG1
- Scientific DescriptionBcl2 (B cell chronic lymphatic leukemia protein 2) is a proto-oncogen, which can contribute to tumorigenesis by counteracting apoptosis in various cell types. The anti-apoptotic effect of Bcl2 is performed by its interactions with suppressors and agonists of cell death and under physiological conditions it is regulated by proteolytic processing and phosphorylation. Bcl2 expression can be detected mainly in lymphoid tissues and in the basal cells of epithelial tissues. It is also a marker that can help in classification of lymphoproliferative diseases and in prognostics of some epithelial neoplasms.
- ReactivityHuman, Mouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203