Anti-Hu CD107a Purified Azide Free

EXBIO

Anti-Hu CD107a Purified Azide Free

7

Western blotting: Recommended dilution: 1 microg/ml. Immunohistochemistry: Recommended dilution: 2-8 microg/ml. Flow cytometry: Intracellular and extracellular staining; recommended dilution: 1-12 microg/ml.

Flow Cytometry, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin

Research Use Only

H4A3

1 mg/ml

IgG1

CD107a (lysosome-associated membrane protein-1, LAMP-1), together with LAMP-2, is a major constituent of lysosomal membrane, 1-2% of total CD107a is found also on the plasma membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes. Increased CD107a immunoreactivity is observed in neurones, and in glial cells surrounding senile plaques in Alzheimers disease cases and is localized mainly in medullary epithelial cells, single macrophages and lymphocytes in acute thymic involution. CD107a is a good marker of mast cell activation.

2°C to 8°C

12352203